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Scar Trials

User Trial Summary, Ayton-Moon, Somerset, UK, 2002

Objective: To rate the ability of Bio-Oil to improve the appearance of scars in user trial.

Sample: 82 participants including adults and children. Scar ages: newly formed to more than 10 years old. Scar types: Raised, flat and depressed scars, ranging from minor burns and grazes to surgical scars.

Method: Product was applied 3 times daily for 4 weeks. Participants instructed to massage in a circular motion until fully obsorbed. Interviews conducted at 0,2 and 4 weeks. Participants rated the improvement they saw on a scale of 1-9 (1 representing 'no improvement and 9 representing 'much improvement').

Result: 82% of participants recorded an improvement in the appearance of their scars after 4 weeks.

Full Trial pdf

Photobiology Laboratory of the Medical University of South Africa, 2005

Objective: To assess the efficacy of Bio-Oil in improving the appearance of scars.

Sample: 24 Participants (22 female and 2 male) aged 18-60.Scar ages: newly formed to 3 years old. Scar types: various ranging from minor burns to surgical scar (12 major scars, 14 minor scars - one participant had 3 scar sites.

Method: Single-blind (assessor), randomized and controlled. Paired study design allowing for intra-subject comparison. Subjects had matching scars or scars large enough to allow application to half a scar. Product applied twice daily for 12 weeks to the targeted area. Application performed under supervision at regular intervals. Assessments conducted at 0,4,8 and 12 weeks.

Result: Bio-Oil improved the appearance of scars in both objective and subjective assessments. 65% of subjects recorded an improvement in appearance at 4 weeks.

Full Trial pdf

proDERM Institute for Applied Dermatological Research, Hamburg, Germany, 2010

Objective: To assess the efficacy of Bio-Oil in improving the appearance of scars.

Sample: 36 female participants of varying ethnicities and aged 18-65. Scar ages: newly formed to 3 years old. Scar locations: abdomen, leg, arm, neck, knee, trunk, upper body.

Method: Double-blind, randomized, parallel group. Subjects had matching scars or scars large enough to allow half-half scar application and intra-subject comparison. Product applied twice daily for 8 weeks, no additional massaging performed on the target area. Application performed under supervision at regular intervals. Assessments conducted at 0, 2, 4 and 8 weeks. Different scar parameters as defined in the Patient and Observer Scar Assessment Scale (POSAS) were evaluated.

Result: Bio-Oil is efficacious in improving the appearance of scars. A statistically significant result after only 2 weeks (day 15), evident in 66% of subjects. After 8 weeks (day 57) 92% of subjects showed an improvement, with the extent of the improvement almost triple that at 2 weeks. A continuous improvement of POSAS over the duration of the study.

Full Trial pdf

Peking University First Hospital, Department of Dermatology Acne Scar Study, Beijing, China, 2012

Objective: Assess the efficacy of Bio-Oil in improving the appearance of facial acne scars on Chinese subjects,

Sample: 44 Chinese subjects with newly formed acne scars on the face (<1 year old). Bio-Oil treatment cell included 32 subjects and the no treatment cell included 12 subjects. Age of participants: 14-30.

Method: Randomized, controlled, efficacy grader-blinded. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Product applied twice daily for 10 weeks. Application performed under supervision at regular intervals. Assessments conducted at 0, 4, 8 and 10 weeks included the following: Global scarring score (GSS) assessment by the investigator, measurement of acne scar color/redness using a chromameter, measurement of sebum levels using a sebumeter, documentation of number of comedones and inflammatory lesions by a dermatologist. Subjects also completed self-assessment questionnaires at each visit.

Result: The best result of the clinical grading was in Bio-Oil's ability to reduce the erythema or redness of macular (flat) acne scars, with the overall skin becoming brighter. Results of the self-assessment questionnaire showed that more than 84% of subjects experienced an improvement in the overall condition of their acne scars and more than 90% experienced an improvement in scar color. Acne count and sebum level measurement results showed that using Bio-Oil does not cause or aggravate acne of increase sebum secretion.

Full Trial pdf