Photobiology Laboratory of the Medical University of South Africa, 2011
Objective: To assess the effect of a single application of Bio-Oil to improve stratum corneum (SC) barrier function and hydration.
Sample: 40 female participants of varying ethnicities. Test site: product applied to the volar forearm of all subjects.
Method: Assessment of skin hydration with a Corneometer as the primary measure, assessment of barrier function with a Vapometer as a secondary measure. Panelists washed their forearms with soap 2 hours before measurements were taken. Baseline instrumental measurements were taken. Bio-Oil and a reference oil were then applied to separate sites on the volar forearm of all subjects. Measurements were taken again immediately after product application as well as 2 hours later, before and after wiping the products off. A control untreated site was also measured at all time points.
Result: After immediate application, both oils reduced transepidermal water loss (TEWL) compared to the no treatment control. Increased skin capacitance values at the 2 hour pre-wipe time point indicated increased skin hydration for both oils. 2 hours later, after wiping the oils from the skin's surface, Bio-Oil showed further increased TEWL values compared to the reference oil, indicating increased moisture release and therefore increased skin hydration.
Full Trial pdf
Objective: To assess the effect of twice daily application of Bio-Oil for moisturization performance and relief of dry skin.
Sample: 25 female Caucasian participants. Test site: product applied to the outer, lower leg of all subjects.
Method: Soap was used to induce dry skin over a 7 day period. Bio-Oil and a reference oil were applied twice daily. Skin assessments were made on days 1 and 3. Visual evaluations were performed by a trained visual evaluator using a 2x magnifying lamp. A control untreated site was also evaluated at all time points.
Result: Both Bio-Oil and the reference oil improved skin dryness compared to the no treatment control. Bio-Oil was statistically superior on day 3. Significant improvements in visual appearance of skin sites treated with Bio-Oil confirmed its effectiveness in relieving dry skin.
Full Trial pdf