Thomas J. Stephens & Associates, Inc., Texas, USA, 2011
Objective: To evaluate the efficacy of Bio‑Oil when used on the décolletage, lower leg and arm by women with mild to moderate photodamaged (ageing) skin.
Sample: 67 female participants, of varying ethnicities, with clinically determined mild to moderate photo damage on the face and neck. Bio-Oil treatment cell included 35 subjects and the no treatment cell included 32 subjects. Age of participants: 30-70.
Method: Randomized, controlled, efficacy grader blinded. Bio‑Oil applied twice daily for 12 weeks on the décolletage, lower leg and arm of participants. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Application was performed under supervision at the baseline visit and clinical evaluations were conducted at 0, 2, 4, 8 and 12 weeks.
Result: Bio‑Oil is efficacious in improving the overall appearance of photodamaged (ageing) skin on the body. After 4 weeks a statistically significant result was achieved for all clinically graded efficacy parameters. After 12 weeks, 89% of subjects in the Bio‑Oil treatment cell showed a statistically significant improvement in overall appearance of the décolletage, lower legs and arms.
Full Trial pdf